Author

Giovanni Barra

ORCID 0009-0000-1343-0876Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:structural biology· 1

Frequent Co-Authors

Alessia RuggieroiD· 1 shared Hwa‐Jung KimiD· 1 shared Maria Carmina ScalaiD· 1 shared Marina SalaiD· 1 shared Pietro CampigliaiD· 1 shared Rita BerisioiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

Alessia RuggieroORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintDec 11, 2025

Structural studies of mycobacterial HptG reveal a silent state and offer insights into TLR4 activation

Giovanni Barra, Marina Sala, Maria Carmina Scala…·Rita Berisio

This study presents the first crystal structure of HtpGMtb, revealing a conformationally silent dimer and direct TLR4 interaction, providing insights into its catalytic activity and TLR4 activation mechanism.

DOI 10.64898/2025.12.11.693645

structural biologyexperimental assay

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