Akhil Shukla

This study shows IL-15R restrains tumor immune surveillance but is dispensable for IL-15-dependent tumor growth control, while IL-15 has minimal role in spontaneous tumor development.

This study shows that NLRC5 expression in tumor cells enhances MHC-I and promotes antitumor immunity by activating immune cells and shaping the tumor microenvironment.

This study shows NLRC5 is essential for tumor immune surveillance and immunoediting, as its deficiency leads to increased tumor growth and reduced immune control.

The paper uses SILAC proteomics to show SOCS1 modulates 181 proteins in Hepa1-6 cells, with UBE2D being a key target involved in MET receptor regulation.