Tavus Atajanova

This study designs protease-activatable cytokine prodrugs to reduce toxicity while maintaining antitumor efficacy in tumor models.

This paper describes a designed IL-21 mimic, 21h10, which shows potent antitumor activity in multiple models and reduces toxicity through TNF blockade.

This study shows that lateral cell polarization, mediated by Lgl, is essential for epithelial organization in sea anemone embryos and aggregates.