Author

Minzhi Liang

University of Notre DameORCID 0009-0000-4665-5959Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Adrian ChaoiD· 2 shared Xin LüiD· 2 shared Courtney Khong· 1 shared Éva SzegezdiiD· 1 shared Gaeun KimiD· 1 shared Guoqiang LiuiD· 1 shared Hyunsu JeoniD· 1 shared James Johnston· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

Adrian ChaoORCID

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2 papers

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedJul 1, 2026

Synthetic essentiality of TRAIL/TNFSF10 in VHL-deficient renal cell carcinoma

Xuechun Wang, Yujing Qin, Loan Duong…·Éva Szegezdi

This study identifies TRAIL as a synthetic essentiality in VHL-deficient ccRCC, showing its regulation by HIF2 and its role in cell proliferation through the p38 MAPK pathway, suggesting a combination therapy strategy.

DOI 10.1073/pnas.2535452123

humanbulk RNA-seq

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BioengineeringJournal of Extracellular VesiclesPeer-reviewedFeb 1, 2026

M1 Macrophage-Derived Small Extracellular Vesicles as Synergistic Nanotherapeutics: Harnessing Intrinsic Anticancer Activity and Drug Delivery Capacity

Gaeun Kim, Hyunsu Jeon, Adrian Chao…·Yichun Wang

This study demonstrates that M1 macrophage-derived small extracellular vesicles (sEVs) act as dual-action nanotherapeutics by combining innate immune-regulatory functions with drug delivery, achieving synergistic anticancer effects.

3 citationstop 4%

humanproteomics

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