Rupesh Balaji Jayachandran

The paper determines the structure of C-type lectins in Aedes aegypti, revealing a conserved dimeric arrangement that facilitates carbohydrate recognition in vector-pathogen interactions.

The paper presents cryo-EM structures of henipavirus nucleoprotein in RNA-bound and RNA-free states, revealing conformational changes that may facilitate genome access without disrupting the nucleocapsid.

This study engineers multivalent antibody fragments, resolves their crystal structures, and shows diabodies can enhance crystallization of antibody-antigen complexes.