Easton R. van Luik

This study identifies pervasive transcriptional remodeling in the dorsolateral prefrontal cortex of individuals with Tourette disorder, highlighting stress-related gene activation in multiple cell types.

This study shows that elevated prefrontal 5-HT2A receptors contribute to tic development in TS and that pimavanserin reduces tic-like behaviors and aggression in mouse models.

The paper introduces a naive Bayes classifier to automate grooming behavior analysis in mice using force-plate actometry, achieving high accuracy and demonstrating its utility in tic disorder models.