Collin J. Anderson

OpenStride: an inexpensive, open-source force plate actometry system for quantification of rodent motor activity and behaviour

OpenStride is an open-source, low-cost force plate actometry system for quantifying rodent motor activity and behaviour, offering reliable tracking and analysis of various movement metrics.

Viral vector-mediated SLC9A6 gene replacement reduces cerebellar dysfunction in the shaker rat model of Christianson syndrome

This study shows that viral vector-mediated SLC9A6 gene replacement improves cerebellar dysfunction and motor phenotypes in shaker rats with Christianson syndrome.

Tic-related behaviors in Celsr3 mutant mice are contributed by alterations of striatal D3 dopamine receptors

The paper investigates how Celsr3 mutations affect tic-like behaviors in mice by examining striatal dopamine receptor alterations.

A novel naive Bayes approach to identifying grooming behaviors in the force-plate actometric platform

The paper introduces a naive Bayes classifier to automate grooming behavior analysis in mice using force-plate actometry, achieving high accuracy and demonstrating its utility in tic disorder models.

Slc9a6 mutation causes Purkinje cell loss and ataxia in the shaker rat

The paper identifies a Slc9a6 mutation causing Purkinje cell loss and ataxia in shaker rats and shows gene therapy can reverse the phenotype.

Targeting Staufen 1 with antisense oligonucleotides for treating ALS and SCA2

This paper develops antisense oligonucleotides targeting STAU1 to treat ALS and SCA2, showing efficacy in reducing STAU1 expression and improving disease markers in mouse models.

Defining the impact of deep brain stimulation contact size and shape on neural selectivity

This study investigates how the size and shape of deep brain stimulation contacts affect neural selectivity, finding that smaller contacts better constrain activation to nearby grey matter but are less energy efficient.

Neural Selectivity, Efficiency, and Dose Equivalence in Deep Brain Stimulation through Pulse Width Tuning and Segmented Electrodes.

This study investigates how pulse width tuning and segmented electrodes affect deep brain stimulation, finding that long pulse widths reduce side effects and improve battery efficiency.