Annie Kathuria

The paper introduces the Neural Impact Score (NIS) to evaluate drug effects on brain organoids across multiple biological categories, demonstrating its utility in cross-species drug benchmarking.

This study uses human iPSC-derived prefrontal cortex organoids to show that THC exposure disrupts neurodevelopmental gene expression and epigenetic regulation, linking these changes to autism risk genes.

This study shows that senescent bone cells' secretome causes spatially varied ECM changes and mechanical weakness in human brain organoids.

This paper introduces Multi-Region Brain Organoids (MRBOs) that integrate cerebral, mid/hindbrain, and complex endothelial components, revealing new roles for endothelial cells in brain development.