Alan Y. Liu

This study investigates how modulating the Rho-ROCK pathway in microfracture clots can reprogram cells to promote chondrogenic rather than fibrotic repair in cartilage defects.

The paper shows that exogenous sphingomyelinase increases MSC-derived EV yield and alters their cargo, enhancing therapeutic effects in a murine wound model.

This study shows that senescent bone cells' secretome causes spatially varied ECM changes and mechanical weakness in human brain organoids.

This study identifies time-dependent mechanical changes in senescent osteocytes, linking them to impaired mechanosensation and bone fragility.