Author

Anannya Kshirsagar

Johns Hopkins UniversityORCID 0009-0009-7519-3226Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:scRNA-seq· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Annie KathuriaiD· 2 shared Sai KulkarniiD· 2 shared Alan Y. LiuiD· 1 shared Chanul KimiD· 1 shared Christian E. BadriD· 1 shared Elizabeth Gomez Flores· 1 shared Hayk MnatsakanyaniD· 1 shared James L. KirklandiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBioengineering

Annie KathuriaORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintAug 11, 2025

Paracrine Bone-Derived Senescent Secretome Induces Spatially Patterned ECM and Biomechanical Vulnerability in Human Brain Organoids

Chanul Kim, Luke Daniel Ofria, Anannya Kshirsagar…·Maryam Tilton

This study shows that senescent bone cells' secretome causes spatially varied ECM changes and mechanical weakness in human brain organoids.

DOI 10.1101/2025.08.11.669674

humanbulk RNA-seq

𝕏 PostBluesky

BioengineeringbioRxivPreprintJan 20, 2025

Multi-Region Brain Organoid: Fusion Organoid with Cerebral, Endothelial and Mid-Hindbrain Components

Anannya Kshirsagar, Hayk Mnatsakanyan, Sai Kulkarni…·Annie Kathuria

This paper introduces Multi-Region Brain Organoids (MRBOs) that integrate cerebral, mid/hindbrain, and complex endothelial components, revealing new roles for endothelial cells in brain development.

DOI 10.1101/2025.01.20.633788

𝕏 PostBluesky