Chan Seok Lim

This study determines the cryo-EM structures of CD28 and CTLA-4 interacting with B7-family ligands on membranes, revealing how membrane geometry and ligand binding affect immune checkpoint signaling.

This study shows tau protein binds DNA, forms condensates, and localizes to centromeres, suggesting a new role in mitosis and cell division.

This paper introduces a deep-learning method to predict spatially varying bending stiffness of biopolymers, showing high accuracy and revealing stiffness variations in filopodia and microtubules.