Author

Husam Khaled

Montreal Clinical Research InstituteORCID 0009-0000-7205-4380Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Alfred Kihoon Lee· 2 shared Benjamin FelleriD· 2 shared Hideto TakahashiiD· 2 shared Nayoung YiiD· 2 shared Nicolas ChoffletiD· 2 shared Aurélie FalloniD· 1 shared Irina ShlaiferiD· 1 shared Phuong Trang NguyeniD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Alfred Kihoon Lee

Mutual co-authors in cluster

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2 papers

Recent·Most cited

NeuroscienceCellsPeer-reviewedApr 4, 2023

α-synuclein preformed fibrils bind to β-neurexins and impair β-neurexin-mediated presynaptic organization

Benjamin Feller, Aurélie Fallon, Wen Luo…·Hideto Takahashi

This study identifies β-neurexins as presynaptic proteins that bind to α-synuclein preformed fibrils, impairing presynaptic organization and contributing to synucleinopathy pathology.

24 citations

humanproteomics

𝕏 PostBluesky

NeuroscienceLife Science AlliancePeer-reviewedJan 25, 2023

SorCS1 inhibits amyloid-β binding to neurexin and rescues amyloid-β-induced synaptic pathology

Alfred Kihoon Lee, Nayoung Yi, Husam Khaled…·Hideto Takahashi

This study shows SorCS1 competes with AβOs for binding to NRX1β, rescuing AβO-induced synaptic dysfunction in neurons.

9 citations

mouseproteomics

𝕏 PostBluesky