Author

Stephen D. Holmes

University of LiverpoolORCID 0009-0000-7262-286XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Edward EmmottiD· 2 shared Aminu S. JahuniD· 1 shared Andrew E. FirthiD· 1 shared Hazel StewartiD· 1 shared Henry G. BarrowiD· 1 shared Iliana GeorganaiD· 1 shared James R. EdgariD· 1 shared Jessica CoomberiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersSystems Biology

Edward EmmottORCID

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintDec 2, 2025

Single-cell phenotypic analysis and multiplet detection through incorporation of microscopy data into cellenONE-based single-cell proteomic data analysis

Markella Loi, Stephen Holmes, Shuxian Zhou…·Edward Emmott

This paper introduces scpImaging, a computational pipeline that uses microscopy data to detect multiplets and improve quality control in single-cell proteomics.

DOI 10.64898/2025.12.01.691577

proteomicsmachine learning (classical)

𝕏 PostBluesky

MicrobiologymBioPeer-reviewedAug 18, 2025

Encephalomyocarditis virus protein 2B* antagonises innate immune signalling by interacting with 14-3-3 protein family members

Samantha K. Nguyen, Nadine Anders, Stephen D. Holmes…·Hazel Stewart

This paper identifies 2B* as an EMCV protein that antagonizes innate immune signaling by interacting with 14-3-3 proteins, specifically through the RRNSS sequence.

5 citations

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𝕏 PostBluesky