Author

Aminu S. Jahun

University of CambridgeORCID 0000-0002-4585-1701Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ian GoodfellowiD· 2 shared Iliana GeorganaiD· 2 shared Myra D.T. HosmilloiD· 2 shared Andrew E. FirthiD· 1 shared Ben WarneiD· 1 shared Christopher J. R. IllingworthiD· 1 shared Edward EmmottiD· 1 shared Effrossyni Gkrania‐KlotsasiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersEvolutionary Biology

Ian GoodfellowORCID

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Author profile →

3 papers

Recent·Most cited

Encephalomyocarditis virus protein 2B* antagonises innate immune signalling by interacting with 14-3-3 protein family members

Samantha K. Nguyen, Nadine Anders, Stephen D. Holmes, Henry G. Barrow, Nina I. Lukhovitskaya, Aminu S. Jahun, Iliana Georgana, Laura G. Caller, James R. Edgar, Stephen C. Graham, Edward Emmott, Andrew E. Firth, Hazel Stewart

This paper identifies 2B* as an EMCV protein that antagonizes innate immune signaling by interacting with 14-3-3 proteins, specifically through the RRNSS sequence.

mBio · Aug 18, 2025Peer-reviewedMicrobiology

Variable rates of SARS-CoV-2 evolution in chronic infections

Ewan W. Smith, William L Hamilton, Ben Warne, Elena R Walker, Aminu S. Jahun, Myra D.T. Hosmillo, Ravindra K. Gupta, Ian Goodfellow, Effrossyni Gkrania‐Klotsas, M. Estée Török, Christopher J. R. Illingworth

This study analyzes within-host SARS-CoV-2 evolution in chronic infections, finding variable rates of evolution and evidence of subpopulation structure.

PLoS Pathogens · Apr 28, 2025Peer-reviewedEvolutionary Biology

Leaked genomic and mitochondrial DNA contribute to the host response to noroviruses in a STING-dependent manner

Aminu S. Jahun, Frédéric Sorgeloos, Yasmin Chaudhry, Sabastine Eugene Arthur, Myra D.T. Hosmillo, Iliana Georgana, Rhys Izuagbe, Ian Goodfellow

This study shows that the cGAS-STING pathway restricts noroviruses by detecting leaked genomic and mitochondrial DNA, leading to IFN responses.

Cell Reports · Mar 1, 2023Peer-reviewedMolecular Biology