Author

Suma Medisetti

University of OttawaORCID 0009-0000-9281-2134Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Pierre A. MattariD· 3 shared David J. PickettsiD· 2 shared José Alex Lourenço FernandesiD· 2 shared Samuel Clémot-Dupont· 2 shared Alena Kalinina· 1 shared Karthik ShekhariD· 1 shared Mohammad Amin Fayaz· 1 shared Rory Stanley· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersDevelopmental Biology

Pierre A. MattarORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintNov 2, 2026

Molecular dissection of the ChAHP complex subunits Adnp and Chd4 reveals common and divergent functions in retinal development

Suma Medisetti, Alena Kalinina, Sujay Shah…·Pierre Mattar

This study investigates the role of the ChAHP complex in retinal development by analyzing Adnp and Chd4 knockouts, revealing shared and distinct functions in cell proliferation and fate.

DOI 10.64898/2026.10.29.762969

mousescRNA-seq

𝕏 PostBluesky

Developmental BiologyDevelopmentPeer-reviewedSep 4, 2025

Chd4 remodels chromatin to control retinal cell type specification and lineage termination

Sujay J. Shah, José Alex Lourenço Fernandes, Suma Medisetti, Pierre A. Mattar

This study shows that Chd4 remodels chromatin to control retinal cell fate by repressing progenitor identity and promoting rod photoreceptor production, without affecting the competence windows for early vs. late cell-type production.

9 citations

mouseATAC-seq

𝕏 PostBluesky

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedJan 14, 2025

The ChAHP chromatin remodelling complex regulates neurodevelopmental disorder risk genes to scale the production of neocortical layers

Samuel Clémot-Dupont, José Alex Lourenço Fernandes, Sarah Larrigan…·Pierre A. Mattar

The paper shows that the ChAHP complex regulates upper-layer neuron production and NDD risk genes during neocortical development through progenitor proliferation and gene regulation.

15 citationstop 2%

mousebulk RNA-seq

𝕏 PostBluesky