José Alex Lourenço Fernandes

This study shows that Chd4 remodels chromatin to control retinal cell fate by repressing progenitor identity and promoting rod photoreceptor production, without affecting the competence windows for early vs. late cell-type production.

The paper shows that the ChAHP complex regulates upper-layer neuron production and NDD risk genes during neocortical development through progenitor proliferation and gene regulation.

The paper identifies self-renewing osteochondral stem cells in the postnatal skeleton and compares their transcriptomes across adult, fetal, mouse, and human samples.

This study shows that temporal identity factors can reprogram adult Muller glial cells and fibroblasts into neurons in mice, using scRNA-seq to validate the transcriptional changes.