Author

Leah M. Black-Holmes

Harvard UniversityORCID 0009-0000-9399-7548Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Dhiraj Suda· 1 shared Dimitris GazgalisiD· 1 shared Felix H. GottliebiD· 1 shared Ilse K. Schaeffner· 1 shared Isidoro TavaresiD· 1 shared Jarrod A. MartoiD· 1 shared Jianwei CheiD· 1 shared Jie JiangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Dhiraj Suda

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1 paper

Recent·Most cited

Cancer BiologyACS Central SciencePeer-reviewedSep 29, 2026

Overcoming EGFR resistance by monovalent and bident inhibitors targeting Cys775

Zhengnian Li, Jie Jiang, Yaning Wang…·Tinghu Zhang

This paper develops covalent EGFR inhibitors targeting cysteine 775 and 797, showing improved efficacy and resistance delay in osimertinib-resistant models.

DOI 10.1021/acscentsci.6c01219

mouseexperimental assay

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