Author
Brigham and Women's HospitalORCID 0000-0003-2086-1134Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Zhengnian Li, Jie Jiang, Yaning Wang…·Tinghu Zhang
This paper develops covalent EGFR inhibitors targeting cysteine 775 and 797, showing improved efficacy and resistance delay in osimertinib-resistant models.
Robert J. Fisher, Kihyun Park, Kwangwoon Lee…·Rhoda M. Alani
The paper shows that inhibiting the CoREST complex with corin alters RNA splicing, increases neoantigen expression, and enhances tumor immunity in melanoma.
Scott B. Ficarro, Deepash Kothiwal, Hyun Jin Bae…·Jarrod A. Marto
This paper evaluates HILIC and ERLIC chromatography for resolving CTD phosphopeptide isoforms, finding ERLIC improves separation of phosphorylated peptides for LC-MS/MS analysis.
Yiling Elaine Chen, Xinzhou Ge, Kyla Woyshner…·Jingyi Jessica Li
APIR aggregates database search algorithms for proteomics to increase peptide identification while controlling FDR, outperforming individual methods on standard and real data.
Yoo Jin Joo, Scott B. Ficarro, Luis Miguel Mendes Soares…·Stephen Buratowski
The paper shows that TAF subunits of TFIID bind downstream promoter DNA during transcription, promoting reinitiation independent of TBP or other factors.