ImmunologybioRxivPreprint
Permissive central tolerance plus defective peripheral checkpoints licence pathogenic memory B cells in CASPR2-antibody encephalitis
Bo Sun, Dominique Fernandes, Anne‐Kathrin Kienzler…·Sarosh R. Irani
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Mayo ClinicORCID 0009-0000-9505-9563Unclaimed ORCID profile · follow to get notified of new preprints
2 papers
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Bo Sun, Dominique Fernandes, Anne‐Kathrin Kienzler…·Sarosh R. Irani
Manoj A. Upadhya, Toni Kirmann, Max A Wilson…·Sukhvir K. Wright
This study shows that LGI1-reactive monoclonal antibodies cause seizures in rats, with molecular and electrophysiological evidence of epileptogenesis.