Author
Toronto Metropolitan UniversityORCID 0009-0001-0543-7418Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Mashiat Zaman, Joshua David, Ayshin Mehrabi…·Timothy E. Shutt
The paper identifies how pathogenic MFN2 variants cause mtDNA release into endosomes and mitochondrial-derived vesicles, triggering inflammation and myopathy, and suggests a therapeutic strategy using integrated stress response activation.
Ayshin Mehrabi, Laura A. Orofiamma, Alyona Ivanova…·Costin N. Antonescu
This study shows AMPK moves early endosomes to mitochondria via Gapex-5 to enhance iron delivery under nutrient scarcity.
Karolina Zak, Nupur Dave, Ayshin Mehrabi…·Costin N. Antonescu
This study shows Nck adaptor proteins regulate clathrin-coated pit dynamics and EGF-stimulated PI3K-Akt signaling, affecting cell proliferation and survival.
Laura A. Orofiamma, Ralph Christian Delos Santos, Ayshin Mehrabi…·Costin N. Antonescu
This study shows AMPK regulates clathrin-mediated endocytosis by controlling Dab2 and Arf6 to selectively internalize β1-integrin.