Colin D.H. Ratcliffe

This study assesses the reproducibility of a 3D spheroid-based assay across four institutes using dual-view oblique plane microscopy and finds high consistency in treatment effects with low technical noise.

The paper uses intravital imaging to study dynamic remodelling of humanised bone marrow-like niches in mice, revealing vascular network formation and collagen matrix changes.

This study shows AMPK regulates clathrin-mediated endocytosis by controlling Dab2 and Arf6 to selectively internalize β1-integrin.

VISIBLE is a system for real-time manipulation and bioprinting of complex in vitro models, enabling precise interventions and improving reproducibility in biomedical research.

This study identifies a reversible basal-like cell state in AKT-inhibitor resistant triple negative breast cancer using multimodal profiling and lineage tracing.