Author
University of CambridgeORCID 0009-0001-1437-1887Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Yuqing Feng, Bismoy Mazumder, Tasuku Konno…·Gabriele S. Kaminski Schierle
This study shows that 24S-HC and 27-HC, brain cholesterol metabolites, cause neuronal dysfunction in human iPSC-derived neurons by disrupting calcium signaling, organelle function, and alpha-synuclein accumulation.
Maria Zacharopoulou, Neeleema Seetaloo, James F. Ross…·Gabriele S. Kaminski Schierle
This study investigates how Ca2+ and Na+ ions affect alpha-synuclein aggregation and fibril polymorphism, revealing their distinct roles in modulating conformational dynamics and structural outcomes.
Marius Brockhoff, Jakob Träuble, Sagnik Middya…·Gabriele S. Kaminski Schierle
The paper introduces PseudoSort, a machine learning algorithm for spike sorting, and applies it to MEA data from hippocampal neurons exposed to monomeric Tau, revealing its impact on neuronal activity.