Author

Alyssa R. Richman

University of VermontORCID 0009-0001-2148-2892Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:Hi-C· 1

Frequent Co-Authors

Joseph R. BoydiD· 2 shared Princess D. RodrigueziD· 2 shared Seth E. FrietzeiD· 2 shared Amrita PalariaiD· 1 shared Anthony J. SaviolaiD· 1 shared David C. BloomiD· 1 shared Donna M. NeumanniD· 1 shared Els VerhoeyeniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Joseph R. BoydORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintDec 29, 2025

IKAROS Gene Regulatory Network Reveal ERG as a Vulnerability in B-cell Acute Lymphoblastic Leukemia

Hana Paculová, Alyssa R. Richman, Joseph Boyd…·Seth E. Frietze

This study identifies ERG as a vulnerability in IKZF1-mutated B-cell acute lymphoblastic leukemia through gene regulatory network analysis and functional validation.

DOI 10.64898/2025.12.29.696402

humanscRNA-seq

𝕏 PostBluesky

MicrobiologymBioPeer-reviewedAug 28, 2025

Multiple long-range cis interactions generate CTCF insulator-dependent viral chromatin domains in quiescent HSV-1 genomes

Alyssa R. Richman, Sophie Kogut, Terri G. Edwards…·Donna M. Neumann

The paper investigates how HSV-1 CTCF insulators regulate chromatin organization and transcription through long-range cis interactions, showing that deletion of the CTRL2 insulator disrupts chromatin domains and alters transcriptional accessibility.

3 citations

virusHi-C

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