Leah M. Whiteman

This paper identifies curli amyloid as a novel activator of the non-canonical inflammasome in dendritic cells, driving hyperactivation without pyroptosis.

This study identifies MMP9+ CD14+ myeloid cells as key drivers of UVB-induced IFN-I-driven inflammation in cutaneous lupus and dermatomyositis through a keratinocyte-fibroblast-myeloid circuit.

This study identifies transcriptomic differences in SLE neutrophils, shows shared ex vivo adaptation with healthy cells, and demonstrates CAR T-cell therapy can reset neutrophil gene expression toward healthy patterns.