Çağla Tükel

This paper identifies curli amyloid as a novel activator of the non-canonical inflammasome in dendritic cells, driving hyperactivation without pyroptosis.

This study shows that Salmonella biofilms contain Z-DNA, which triggers anti-Z-DNA antibody responses in mice, linking bacterial infections and biofilm formation to autoimmune disease.

This study identifies Escherichia coli as a key driver of B cell accumulation in Peyer's patches via CXCR2-dependent mechanisms involving curli amyloid fibers and TLR2 signaling.

This study identifies that Podoplanin-expressing mesenchymal stromal cells release exosomes that trigger SAA3 overproduction in macrophages, leading to cardiac amyloidosis after myocardial infarction.

The paper investigates how human and bacterial amyloids affect enteric glia and smooth muscle cells, finding they trigger a pro-inflammatory response and DNA damage.