Author

Yun Zhang

University of Rochester MedicineORCID 0009-0001-3184-3751Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yun Zhang11 papers · J. Craig Venter Institute

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Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew V. SamuelsoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

1 paper

Recent·Most cited

ImmunologyEMBO ReportsPeer-reviewedOct 2, 2025

Antiviral defense in aged Caenorhabditis elegans declines due to loss of DRH-1/RIG-I deSUMOylation via ULP-4/SENP7

Yun Zhang, Andrew V. Samuelson

This study shows that aging in C. elegans reduces antiviral defense by impairing DRH-1 deSUMOylation via ULP-4, leading to loss of the intracellular pathogen response.

4 citations

C. elegansproteomics

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