Author

Alexander M. Hofer

University of BernORCID 0009-0001-5176-1622Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Organism:C. elegans· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Oliver MühlemanniD· 2 shared Alina C. TeuscheriD· 1 shared Andrea FossatiiD· 1 shared Anita GoyalaiD· 1 shared Collin Y. EwaldiD· 1 shared Cyril StatzeriD· 1 shared Evangelos D. KarousisiD· 1 shared Ingmar SchoeniD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

Oliver MühlemannORCID

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3 papers

Recent·Most cited

Cell BiologyScientific ReportsPeer-reviewedNov 28, 2025

Analysing the effect of full-length and C-terminally truncated progranulin on proliferation, colony formation, and migration in HepG2 and U87 cells

Alexander M. Hofer, Luisa Tobler, Marc‐David Ruepp, Oliver Mühlemann

This study examines how full-length and C-terminally truncated progranulin affects cell proliferation, colony formation, and migration in HepG2 and U87 cells.

DOI 10.1038/s41598-025-26703-9

humanproteomics

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BiochemistryJournal of Biological ChemistryPeer-reviewedMay 28, 2025

Efficient cell-free translation from diverse human cell types

Jana Ziegelmüller, Nikolaos Kouvelas, Nino Schwaller…·Evangelos D. Karousis

The paper presents a scalable method for preparing cell-type-specific lysates from human cell lines to improve cell-free translation systems.

4 citations

humanprotein sequence

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Molecular BiologybioRxivPreprintAug 30, 2022

Mechanotransduction coordinates extracellular matrix protein homeostasis promoting longevity in C. elegans

Alina C. Teuscher, Cyril Statzer, Anita Goyala…·Collin Y. Ewald

The paper identifies hemidesmosome-containing structures that mediate mechanotransduction to regulate ECM homeostasis and promote longevity in C. elegans.

5 citations

C. elegansproteomics

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