James W Sheffield

This study identifies clofarabine as an inhibitor of EPEC pathogenesis by targeting bacterial and host translation, revealing a bacterial mechanism to counteract its effects.

This study isolates a novel phage targeting the LPS inner core of Pseudomonas aeruginosa and shows that LPS modifications create a trade-off in resistance to two phages, suggesting that combining phages targeting different LPS regions can delay resistance.

This study shows that typhoid toxin from Salmonella Typhi triggers DNA damage responses, leading to antimicrobial effects like lysozyme secretion that inhibit bacterial virulence.