Author

Maged T Ghoche

University of PittsburghORCID 0009-0001-6679-681XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Fanen Yuan· 2 shared Kalil G. AbdullahiD· 2 shared Kenji MikiiD· 2 shared Namya ManojiD· 2 shared Pascal Olivier ZinniD· 2 shared Sameer AgnihotriiD· 2 shared Samuel K. McBrayeriD· 2 shared Skyler OkeniD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

Fanen Yuan

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologyCellPeer-reviewedSep 1, 2026

Gliomas phenocopy an inborn error of metabolism to drive neuronal activity and tumor growth

Kalil G. Abdullah, Kenji Miki, Charles K. Edgar…·Samuel K. McBrayer

This study identifies GAA accumulation in gliomas as a driver of neuronal activity and tumor growth, linking cancer metabolism to neuroscience through GABAA receptor activation.

1 citationtop 4%

humanmetabolomics

𝕏 PostBluesky

Cancer BiologybioRxivPreprintFeb 9, 2026

Pharmacological induction of mitochondrial stress counteracts therapy resistance in glioblastoma stem-like cells

Kenji Miki, Maged T Ghoche, Fanen Yuan…·Kalil G. Abdullah

This study shows that doxycycline induces mitochondrial stress and selectively kills glioblastoma stem-like cells, offering a drug repurposing strategy for therapy-resistant gliomas.

2 citations

humanproteomics

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