Author
University of North Carolina at Chapel HillORCID 0009-0001-6845-1284Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Anirban Ghoshal, John D. Sears, Mohammad Anwar Hossain…·Timothy Mark Willson
John D. Sears, Durbadal Ojha, Sharon Taft-Benz…·Nathaniel J. Moorman
This study identifies a first-in-class inhibitor of alphavirus nsP2 helicase activity, showing broad antiviral activity and in vivo efficacy against chikungunya virus.
M. Bose, John D. Sears, Kacey Marie Talbot…·Timothy Mark Willson
This paper identifies and optimizes oxaspiropiperidine inhibitors targeting nsP2hel, showing nanomolar antiviral activity against multiple alphaviruses.
Anirban Ghoshal, Kesatebrhan Haile Asressu, Mohammad Anwar Hossain…·Timothy Mark Willson
The paper identifies potent covalent inhibitors of Chikungunya nsP2 protease and establishes structure-activity relationships to guide inhibitor design.