Durbadal Ojha

This paper identifies reovirus σ3 as a viral protein that induces proteasomal degradation of IKKβ, reducing NF-κB activation and IFN-β expression to enhance viral replication.

This study identifies a first-in-class inhibitor of alphavirus nsP2 helicase activity, showing broad antiviral activity and in vivo efficacy against chikungunya virus.

This paper identifies and optimizes oxaspiropiperidine inhibitors targeting nsP2hel, showing nanomolar antiviral activity against multiple alphaviruses.