Author

Sylvain Caillat

ORCID 0009-0001-8172-6254Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Bernard S. LópeziD· 1 shared Elodie DardillaciD· 1 shared Jean‐Luc RavanatiD· 1 shared Sandrine Ragu· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperCell Biology

Bernard S. LópezORCID

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintFeb 27, 2025

Dysregulation of replication stress-induced ROS in transformed cell lines: a vicious circle at cancer initiation

Sandrine Ragu, Elodie Dardillac, Sylvain Caillat…·Bernard S. López

This study shows that cancer cell lines exhibit dysregulated LoL-DDR, leading to increased RIR and 8-oxoG accumulation, creating a replication stress-ROS vicious circle that promotes tumorigenesis.

1 citation

humanDNA methylation

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