NeuroscienceNeuropsychopharmacologyPeer-reviewed
Incentive Salience, not Psychomotor Sensitization or Tolerance, Drives Escalation of Cocaine Self-Administration in Heterogeneous Stock Rats
Jarryd Ramborger, Joseph Mosquera, Molly Brennan…·Olivier George
The paper identifies incentive salience as the driver of cocaine self-administration escalation in rats, showing individual differences in pre-lever activity predict long-term intake.
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