Elizabeth A. Sneddon

This study performs a GWAS on cocaine self-administration in rats, identifying six genome-wide significant loci, including one linked to carboxylesterase genes involved in cocaine metabolism.

This study shows that higher addiction-like severity in rats predicts prolonged oxycodone withdrawal-induced allodynia, with stronger associations between self-administration behaviors and pain sensitivity.

The paper identifies incentive salience as the driver of cocaine self-administration escalation in rats, showing individual differences in pre-lever activity predict long-term intake.

This study finds that irregular estrous cycles in HS rats are associated with severe cocaine addiction-like behaviors, but estrous phase itself does not influence cocaine self-administration.

This study examines how early life stress combined with adolescent alcohol consumption affects alcohol drinking behaviors in mice, finding that it increases aversion-resistant drinking in females.

The paper shows that escalation of cocaine intake, progressive ratio responding, and continued use despite adverse consequences are highly correlated in rats, with sex differences in addiction-like behaviors.

This study shows female C57BL/6J mice are more resistant to footshock punishment when self-administering ethanol compared to males.

This study shows that in FCG mice, sex hormones and sex chromosomes independently influence ethanol consumption, preference, and relapse-like behavior.