Author

Dhruv Singhal

Beth Israel Deaconess Medical CenterORCID 0000-0002-6300-1647Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

Timothy P. PaderaiD· 3 shared Marla Marquez· 2 shared Anton GulkoiD· 1 shared Brian J. Kinsman· 1 shared Charissa R. KimiD· 1 shared Christopher L. JacobsiD· 1 shared E. R. KorniD· 1 shared Eliza O’Donnell· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersPhysiology

Timothy P. PaderaORCID

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Author profile →

3 papers

Recent·Most cited

Selective Activation of NaV1.3 Restores Lymphatic Contractility in Age and Injury

Katarina J. Ruscic, Reetu Singh, Lingshan Liu, Marla Marquez, Johanna J. Rajotte, Pinji Lei, Olivia D. Miller, Brian J. Kinsman, Meghan J. O’Melia, Dhruv Singhal, James W. Baish, Leigh D. Plant, Timothy P. Padera

This study identifies NaV1.3 as a druggable target in adult lymphatic muscle that can restore contractility in aging and radiation injury.

bioRxiv · Dec 17, 2025 · PreprintPhysiology

Single-nuclear transcriptomics of lymphedema-associated adipose reveals a pro-lymphangiogenic stromal cell population

Gregory P. Westcott, Margo P. Emont, Anton Gulko, Zhibo Zhou, Charissa R. Kim, Gopal Varma, Leo L. Tsai, Eliza O’Donnell, Zinger Yang, Wenle Liang, Christopher L. Jacobs, Linus T.-Y. Tsai, Timothy P. Padera, Dhruv Singhal, Evan D. Rosen

The paper uses single-nuclear RNA sequencing to analyze adipose tissue in lymphedema patients, identifying a stromal cell population that promotes lymphangiogenesis.

bioRxiv · Feb 18, 2025 · PreprintCell Biology

A Multiresolution Approach with Method-Informed Statistical Analysis for Quantifying Lymphatic Pumping Dynamics

Mohammad Sayed Razavi, Katarina Jennifer Ruscic, E. R. Korn, Marla Marquez, Timothy T. Houle, Dhruv Singhal, Lance L. Munn, Timothy P. Padera

This paper develops a multiresolution imaging and analysis approach to quantify lymphatic pumping dynamics, improving measurement reliability across species and conditions.

npj Imaging · Jan 17, 2025Peer-reviewedPhysiology