Author

Gopinath Lakshmanan

Queen Mary University of LondonORCID 0009-0001-9429-2096Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Aarti SinghiD· 1 shared Danilo FaccendaiD· 1 shared Dong Xia· 1 shared Jordi Lopez-TremoledaiD· 1 shared Manuel RigoniD· 1 shared Marta Gramaça Caldeira· 1 shared Michelangelo CampanellaiD· 1 shared Paola GiuntiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Aarti SinghORCID

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1 paper

Recent·Most cited

Cell BiologyPharmacological ResearchPeer-reviewedFeb 19, 2026

Mitochondria drive microglial NRLP3 inflammasome activation via TSPO

Aarti Singh, Manuel Rigon, Tong Guo…·Michelangelo Campanella

This study shows TSPO on mitochondria promotes microglial inflammasome activation by stabilizing NLR proteins, inhibiting mitophagy, and enhancing pro-inflammatory gene expression, leading to excitotoxicity.

6 citationstop 1%

mouseexperimental assay

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