Author

Xiangtian Tan

Herbert Irving Comprehensive Cancer CenterORCID 0009-0001-9808-5959Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrea CalifanoiD· 2 shared Jeremy WorleyiD· 2 shared Alec Wang· 1 shared Alejandro ChaveziD· 1 shared Aleksandar ObradovićiD· 1 shared Andrew HoweiD· 1 shared Beatrice Salvatori· 1 shared Charles G. DrakeiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersSystems Biology

Andrea CalifanoORCID

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintJun 28, 2021

Interrogation of genome-wide, experimentally dissected gene regulatory networks reveals mechanisms underlying dynamic cellular state control

Xiangtian Tan, Jeremy Worley, Mikko M. Turunen…·Andrea Califano

The paper uses CRISPRi and single-cell RNA-seq to reverse engineer gene regulatory networks in colorectal cancer cells, revealing autoregulatory and cooperative mechanisms.

11 citations

humanscRNA-seq

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Systems BiologybioRxivPreprintMay 20, 2021

Systematic, Protein Activity-based Characterization of Single Cell State

Lukas J. Vlahos, Aleksandar Obradović, Jeremy Worley…·Andrea Califano

The paper introduces PISCES, a platform that improves single-cell analysis by estimating protein activity's role in cell state, validated with experimental assays and applied to human tissue data.

26 citations

humanscRNA-seq

𝕏 PostBluesky