Author

Yichen Zhang

Howard Hughes Medical InstituteORCID 0009-0001-9809-4935Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Assay:long-read sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

Ofer RogiD· 2 shared Adam HefeliD· 1 shared Erik M. JørgenseniD· 1 shared James G. Baldwin-BrowniD· 1 shared Kewei XuiD· 1 shared Matthew P. MilleriD· 1 shared Matthew S. RichiD· 1 shared Nitin PhadnisiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenetics

Ofer RogORCID

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2 papers

Recent·Most cited

High-efficiency targeted integration of extrachromosomal arrays in C. elegans using PhiC31 integrase

Matthew S. Rich, Ryan Pellow, Yichen Zhang, Adam Hefel, Ofer Rog, Erik M. Jørgensen

The paper introduces PhIAT, a method using PhiC31 integrase to efficiently integrate extrachromosomal arrays into C. elegans chromosomes, enabling stable genomic modifications.

Science Advances · Oct 7, 2026Peer-reviewedGenetics

Decoding chromosome organization using CheC-PLS: chromosome conformation by proximity labeling and long-read sequencing

Kewei Xu, Yichen Zhang, James G. Baldwin-Brown, Thomas A. Sasani, Nitin Phadnis, Matthew P. Miller, Ofer Rog

The paper introduces CheC-PLS, a proximity-labeling technique that uses Nanopore sequencing to decode chromosome organization by identifying methylated bases along long reads, demonstrating its application in budding yeast.

Journal of genetics and genomics/Journal of Genetics and Genomics · May 17, 2026Peer-reviewedGenomics