Erik M. Jørgensen

The paper introduces PhIAT, a method using PhiC31 integrase to efficiently integrate extrachromosomal arrays into C. elegans chromosomes, enabling stable genomic modifications.

SynaptoTagMe enables in vivo mapping and modulation of neurotransmission at single-cell resolution in C. elegans by fluorescently labeling and ablating vesicular transporters.

The paper introduces PhIT, a recombinase-based method for modular protein tagging in C. elegans, using CRISPR to insert a landing pad and PhiC31 integrase for tag insertion.

This study shows that neuronal β-spectrin/UNC-70 is essential for axon integrity in C. elegans motor neurons throughout their lifespan.

The paper shows mechanical force activates TREK-1 channels via PLD2 and lipid clustering, leading to second messenger signaling and ion flow.

The paper shows that CaV1 and CaV2 calcium channels in C. elegans neuromuscular junctions mediate the release of distinct synaptic vesicle pools.

The paper shows that Dynamin 1xA forms molecular condensates with Syndapin 1 at endocytic sites, enabling ultrafast endocytosis by bypassing the recruitment step.

The paper shows that the Habc domain of syntaxin is required for Unc18 to open, enabling SNARE complex formation in synaptic transmission.

The paper presents C. elegans strains with constitutively expressed Cas9 from integrated transgenes, significantly improving CRISPR editing efficiency and reducing workload.

SynapsEM is a computer program that automates synapse morphometry by recording coordinates from segmented structures and calculating synaptic parameters in Matlab.

The paper studies synaptic vesicle dynamics at mouse hippocampal synapses, showing rapid and reversible recruitment of vesicles to release sites after action potentials.

This study identifies NCA-1 and NCA-2 as downstream targets of the Gq/Rho pathway in C. elegans, showing their role in regulating locomotion through neuronal activity.