Author

Jichen Wen

ORCID 0009-0002-0165-6901Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adam Štefek· 1 shared Alexandra M. HamiD· 1 shared Alham Saadat· 1 shared Amelia Weber HalliD· 1 shared Amit V. KheraiD· 1 shared Benjamin SchmandtiD· 1 shared Cassandra WhiteiD· 1 shared Charles B. EpsteiniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Adam Štefek

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1 paper

Recent·Most cited

The 9p21.3 Coronary Artery Disease Risk Locus Modulates Vascular Cell-State Transitions via Enhancer-Driven Regulation of MTAP

Timothy N. Audam, Benjamin Schmandt, Yi Huang, Young Beum Cho, Mayank Murali, Rama Kaalia, Saaket Agrawal, Jinping Liu, Hongjie Shi, Zhou Yuan, Dengwei Cao, Lan Jiang, Yun Li, Jichen Wen, Zhao Hongqiang, , Melina Claussnitzer

This study identifies 12 enhancers in the 9p21.3 CAD risk locus that regulate MTAP, modulating vascular cell-state transitions and CAD risk through stress-responsive mechanisms.

bioRxiv · Nov 18, 2025 · PreprintGenomics