Author

Rama Kaalia

Broad InstituteORCID 0000-0002-1305-0774Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Hesam DashtiiD· 2 shared Mayank MuraliiD· 2 shared Melina ClaussnitzeriD· 2 shared Adam Štefek· 1 shared Alexandra M. HamiD· 1 shared Alham Saadat· 1 shared Amelia Weber HalliD· 1 shared Amit V. KheraiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetic & Genomic Medicine

Hesam DashtiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genome-Wide Discovery Reveals Adipose-Specific and Systemic Regulators of Insulin Resistance

Mario García‐Ureña, Pearlyn Jia Ying Toh, Raquel Martínez, Rama Kaalia, Mayank Murali, Hesam Dashti, Yaxin Jing, César Cunha, María J Romero-Lado, Yuejiao Huang, Martin Wabitsch, Melina Claussnitzer, Tuomas O. Kilpeläinen

This study identifies 282 genetic loci associated with insulin resistance through multi-trait GWAS, highlighting adipose-specific and systemic regulators and potential therapeutic targets.

medRxiv · Apr 1, 2026 · PreprintGenetic & Genomic Medicine

The 9p21.3 Coronary Artery Disease Risk Locus Modulates Vascular Cell-State Transitions via Enhancer-Driven Regulation of MTAP

Timothy N. Audam, Benjamin Schmandt, Yi Huang, Young Beum Cho, Mayank Murali, Rama Kaalia, Saaket Agrawal, Jinping Liu, Hongjie Shi, Zhou Yuan, Dengwei Cao, Lan Jiang, Yun Li, Jichen Wen, Zhao Hongqiang, , Melina Claussnitzer

This study identifies 12 enhancers in the 9p21.3 CAD risk locus that regulate MTAP, modulating vascular cell-state transitions and CAD risk through stress-responsive mechanisms.

bioRxiv · Nov 18, 2025 · PreprintGenomics

Refining modules to determine functionally significant clusters in molecular networks

Rama Kaalia, Jagath Chandana Rajapakse

The paper introduces a modular refinement algorithm to detect smaller, functionally significant modules in protein-protein interaction networks that classical methods miss.

BMC Genomics · Dec 1, 2019Peer-reviewedBioinformatics