Author

Madigan M. Reid

Gladstone InstitutesORCID 0009-0002-0177-0691Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

Andrew C. YangiD· 2 shared Akira KunitomiiD· 1 shared Alexander Gerschmann· 1 shared Alexis J. CombesiD· 1 shared Andrey S. KlymchenkoiD· 1 shared Ankita Talukdar· 1 shared Antonia Clarissa WehniD· 1 shared Bernhard Groschup· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Andrew C. YangORCID

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2 papers

Recent·Most cited

Cerebral microthrombi promote focal Cav-1-dependent blood-brain barrier impairment, triggering neuroinflammation and neuronal damage after traumatic brain injury

Antonia Clarissa Wehn, Martina Schifferer, Joshua James Shrouder, Ankita Talukdar, Morgane Louessard, Myriam Abioui-Mourgues, Valeria Jose Boide-Trujillo, Gian-Marco Calandra, Bernhard Groschup, Madigan M. Reid, Jane Oberhauser, Uta Mamrak, M-L. Fleury, Pauline Marie, Fereniki Moschogiannaki, , Igor Khalin

This study identifies cerebral microthrombi as focal sites of Cav-1-dependent BBB dysfunction after TBI, linking microvascular thrombosis to neuronal damage through transcytosis.

bioRxiv · Oct 14, 2026 · PreprintNeuroscience

Temporal AI model predicts drivers of cell state trajectories across human aging

Javier Gómez Ortega, Rangarajan D. Nadadur, Akira Kunitomi, Steven Kothen-Hill, Julian U G Wagner, Sarp Kurtoglu, Bumjoon Kim, Madigan M. Reid, Thomas Lu, Kaho Washizu, Lukas Zanders, Han Chen, Yujie Zhang, Sarah Ancheta, Sara Lichtarge, , Christina V. Theodoris

The paper introduces a temporal AI model, MaxToki, trained on extensive gene data to predict cell state changes across human aging and identifies age-modulating targets.

bioRxiv · Apr 1, 2026 · PreprintBioinformatics