Author

Jane Oberhauser

Gladstone InstitutesORCID 0000-0001-9792-0441Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Andrew C. YangiD· 2 shared Aja PraganaiD· 1 shared Alexander Gerschmann· 1 shared Alina IsakovaiD· 1 shared Andrey S. KlymchenkoiD· 1 shared Angela E. Madira· 1 shared Ankita Talukdar· 1 shared Anna DongiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersNeuroscience

Andrew C. YangORCID

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3 papers

Recent·Most cited

Cerebral microthrombi promote focal Cav-1-dependent blood-brain barrier impairment, triggering neuroinflammation and neuronal damage after traumatic brain injury

Antonia Clarissa Wehn, Martina Schifferer, Joshua James Shrouder, Ankita Talukdar, Morgane Louessard, Myriam Abioui-Mourgues, Valeria Jose Boide-Trujillo, Gian-Marco Calandra, Bernhard Groschup, Madigan M. Reid, Jane Oberhauser, Uta Mamrak, M-L. Fleury, Pauline Marie, Fereniki Moschogiannaki, , Igor Khalin

This study identifies cerebral microthrombi as focal sites of Cav-1-dependent BBB dysfunction after TBI, linking microvascular thrombosis to neuronal damage through transcytosis.

bioRxiv · Oct 14, 2026 · PreprintNeuroscience

Multi-modal choroid plexus pathology in aging and Alzheimer's disease

Huixin Xu, Peter Lotfy, Benjamin Englert, Jane Oberhauser, Lillian I.J. Byer, Jasmin Wihlman, Kia Colangelo, Serhat Vahip Okar, Ashley A. Thommana, Henri A. J. Puttonen, Mikko I. Mäyränpää, Jarno Tuimala, Rute M. S. M. Pedrosa, Darshan Kumar, James Haberberger, , Maria K. Lehtinen

This study creates a multi-modal atlas of choroid plexus pathology across aging and Alzheimer's disease, identifying fibrosis, calcification, and macrophage abnormalities as key features.

bioRxiv · Jan 1, 2026 · PreprintNeuroscience

Single-soma transcriptomics of tangle-bearing neurons in Alzheimer's disease reveals the signatures of tau-associated synaptic dysfunction

Marcos Otero‐García, Sameehan Uday Mahajani, Debia Wakhloo, Weijing Tang, Yue-Qiang Xue, Samuel Morabito, Jie Pan, Jane Oberhauser, Angela E. Madira, Tamara Shakouri, Yongning Deng, Thomas F. Allison, Zihuai He, William E. Lowry, Riki Kawaguchi, , Inma Cobos

The paper identifies gene expression signatures in Alzheimer's disease neurons with tau aggregates, revealing shared and subtype-specific molecular changes related to synaptic function and metabolism.

Neuron · Jul 25, 2022Peer-reviewedNeuroscience