Author

Andreea Grãdinaru

Institute of Genetics and CancerORCID 0009-0002-0451-3615Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Anabel Martinez LyonsiD· 2 shared Edward J. JarmaniD· 2 shared Kyle Davies· 2 shared Luke BoulteriD· 2 shared Paula OlaizolaiD· 2 shared Scott H. WaddelliD· 2 shared Timothy James KendalliD· 2 shared Yuelin YaoiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersCancer Biology

Anabel Martinez LyonsORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 22, 2025

Epithelial state-transitions permit inflammation-induced tumorigenesis.

Edward J. Jarman, Anabel Martinez Lyons, Yuelin Yao…·Luke Boulter

This study identifies epithelial state transitions driven by inflammation that promote tumorigenesis, showing that targeting NOTCH signaling can prevent pre-neoplastic to neoplastic transition.

DOI 10.1101/2025.06.22.660911

mousebulk RNA-seq

Cell BiologybioRxivPreprintApr 21, 2025

Tissue scarring provides a biomechanical framework to promote mammalian bile duct regeneration through the activation of integrin-SRC/FAK signalling.

Alexander Walker, Paula Olaizola, Euan Brennan…·Luke Boulter

This study shows that collagen scar formation during bile duct regeneration alters biomechanical properties, activating integrin-SRC/FAK signaling to drive ductular regeneration through a leading-tip of integrin-2-high cells.

1 citation

mousescRNA-seq