Author

Anabel Martinez Lyons

Edinburgh Napier UniversityORCID 0000-0001-6455-7172Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Andreea GrãdinaruiD· 2 shared Edward J. JarmaniD· 2 shared Kyle Davies· 2 shared Luke BoulteriD· 2 shared Paula OlaizolaiD· 2 shared Scott H. WaddelliD· 2 shared Timothy James KendalliD· 2 shared Yuelin YaoiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersCancer Biology

Andreea GrãdinaruORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 3, 2026

Cholesterol and p53 promote senescence and systemic fibrosis in metabolic dysfunction-associated steatohepatitis

Celine I Wittke, Dale M. Watt, Liam Butler…·Timothy J. Humpton

This study shows that p53 and cholesterol drive liver fibrosis and systemic fibrosis in MASH, with sex-specific effects in mice.

DOI 10.64898/2026.09.02.748892

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJun 22, 2025

Epithelial state-transitions permit inflammation-induced tumorigenesis.

Edward J. Jarman, Anabel Martinez Lyons, Yuelin Yao…·Luke Boulter

This study identifies epithelial state transitions driven by inflammation that promote tumorigenesis, showing that targeting NOTCH signaling can prevent pre-neoplastic to neoplastic transition.

DOI 10.1101/2025.06.22.660911

mousebulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintApr 21, 2025

Tissue scarring provides a biomechanical framework to promote mammalian bile duct regeneration through the activation of integrin-SRC/FAK signalling.

Alexander Walker, Paula Olaizola, Euan Brennan…·Luke Boulter

This study shows that collagen scar formation during bile duct regeneration alters biomechanical properties, activating integrin-SRC/FAK signaling to drive ductular regeneration through a leading-tip of integrin-2-high cells.

1 citation

𝕏 PostBluesky