Shobina Premachandran

This study shows that PINK1 in myeloid cells represses mtDNA release and immune signaling, which contributes to neuronal pathology in Parkinson's disease models.

This study identifies early immune dysregulation in PINK1 KO mice following intestinal infection, showing myeloid cell activation and T cell response as key factors in PD-like disease progression.

The paper identifies four subpopulations of human choroid plexus epithelial cells, including TYRP1-high cells with distinct molecular features related to pigmentation, cell cycling, and stress.

This study characterizes dopaminergic neurons in the gut using a DAT-cre reporter mouse line, revealing distinct subtypes with dual-transmitter content.