Sai Rupini Vemuri

Active Site Heterogeneity Drives Differential Sialic Acid Metabolism in Enterobacteriaceae Pathogens

This study investigates how differences in active site structures of the NanA enzyme affect sialic acid metabolism in Enterobacteriaceae pathogens, revealing implications for pathogenicity and therapeutic targets.

Intracellular calcium dysregulation precedes muscle decline in C. elegans modeling Duchenne muscular dystrophy

This study shows that sarcoplasmic calcium dysregulation occurs before structural muscle damage in C. elegans modeling Duchenne muscular dystrophy and that increased activity can improve some muscular parameters but not longevity.