Harish Babu Kolla

Phylogenetic Analysis of cpn60 UT region reveal oligonucleotide regions for the detection of prominent Enterobacteriaceae pathogens

This study identifies oligonucleotide regions in the cpn60 UT region for detecting Enterobacteriaceae pathogens using real-time PCR.

Co-administration of Staphylococcus aures Fibronectin Binding Protein A N1-3 region and Lipoteichoic acid antigen mixture enhance antibody response in BALB/c mice

This study evaluates a multi-antigen vaccine strategy using FnBPA and LTA in BALB/c mice, showing enhanced antibody response and survival against S. aureus.

Unleashing the Immune Arsenal: Development of Broad-spectrum Multiepitope Bluetongue Vaccine Targeting Conserved T Cell Epitopes of Structural Proteins

This paper develops a broad-spectrum multiepitope vaccine for bluetongue virus targeting conserved T cell epitopes in structural proteins, showing strong binding and potential for inducing immune responses.

Active Site Heterogeneity Drives Differential Sialic Acid Metabolism in Enterobacteriaceae Pathogens

This study investigates how differences in active site structures of the NanA enzyme affect sialic acid metabolism in Enterobacteriaceae pathogens, revealing implications for pathogenicity and therapeutic targets.

Targeted αGalCer/CD1d Therapy Engages Invariant Natural Killer T Cells to Facilitate Cardiac Healing in Chronic Doxorubicin-Induced Cardiomyopathy

This study investigates the role of iNKT cells in cardiac healing using GalCer/CD1d therapy in a Doxorubicin-induced cardiomyopathy model, finding increased IFN-γ and IL-10 without worsening cardiac damage.

In vivo Protective Efficacy of Emodin in Swiss Albino Mice Induced with Dalton Ascitic Lymphoma

This study evaluates emodin's therapeutic effect on Dalton ascitic lymphoma in mice, showing it outperforms methotrexate and meets Lipinski's rule of 5 for drug candidacy.

Immuno-informatics Study Identifies Conserved T Cell Epitopes in Non-structural Proteins of Bluetongue Virus Serotypes: Formulation of Computationally Optimized Next-Generation Broad-spectrum Multiepitope Vaccine

The paper identifies conserved T cell epitopes in Bluetongue Virus non-structural proteins and evaluates their potential as a broad-spectrum vaccine using computational methods.

Advancing Tolerogenic Immunotherapy: A Multi-Epitope Vaccine Design Targeting the CYP2D6 Autoantigen in Autoimmune Hepatitis Through Immuno-Informatics

This paper designs a multi-epitope tolerogenic vaccine targeting CYP2D6 for autoimmune hepatitis using immuno-informatics, showing it induces IL-10 and programs dendritic cells toward a tolerogenic state.

In Vitro Anti-cancer potential of Aloe emodin against Oral Squamous Cell Carcinoma

This study evaluates the anti-cancer effects of Aloe emodin on oral squamous cell carcinoma cells using in vitro assays.