Alex Proekt

Comprehensive 3D mapping reveals distinct spatial gradients of SST, PV, and TH interneurons across the mouse caudoputamen

The paper creates a 3D atlas of SST, PV, and TH interneurons in the mouse caudoputamen, revealing distinct spatial distributions across striatal territories.

A transposase-derived gene required for human brain development

This study identifies PGBD5 as a transposase-derived gene essential for brain development in humans and mice, with deficiency causing intellectual disability and seizures.

Convergent Control of NREM Sleep and Anesthesia by Prefrontal Layer 5 Extratelencephalic Neurons

This study identifies prefrontal cortical neurons that regulate both NREM sleep and anesthesia by modulating their activity and connectivity.

Changes in brain connectivity and neurovascular dynamics during dexmedetomidine-induced loss of consciousness

This study examines changes in brain connectivity and neurovascular dynamics during dexmedetomidine-induced unconsciousness and recovery, finding widespread connectivity decreases and cerebellum-specific increases in structure-function coupling.

Neural assemblies coordinated by cortical waves are associated with waking and hallucinatory brain states

The paper shows that cortical waves coordinate neuronal assemblies in waking and dissociated states, with external stimuli eliciting similar patterns in wakefulness but not under anesthesia.

Weak Coupling Between Spontaneous Local Cortical Activity State Switches Under Anesthesia Leads to Strongly Correlated Global Cortical States

The paper shows that cortical state transitions under anesthesia are local and weakly coupled, not driven by subcortical inputs.

Visual evoked feedforward-feedback travelling waves organize neural activity across the cortical hierarchy in mice

The paper demonstrates visual evoked traveling waves in awake mice, showing feedforward and feedback waves coordinate neural activity across the cortical hierarchy.

Learning to read the imprints of consciousness on global brain dynamics: an application to intra-operative monitoring of anesthesia

This paper develops a method to monitor anesthesia depth by analyzing brain dynamics, showing it can distinguish between awake and unconscious states with high accuracy.