BiophysicsbioRxivPreprint
Superhelicase-driven isothermal amplification of repetitive and low-complexity DNA
Fahad Rashid, Jimin Kang, Tiantian Shang…·Taekjip Ha
This study demonstrates that SHARP, a helicase-driven isothermal amplification method, effectively amplifies repetitive and compositionally extreme DNA sequences that are challenging for conventional PCR.